Factors predicting in-breast tumor recurrence after breast-conserving surgery

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Local recurrence after breast-conserving surgery for breast cancer.

Local recurrence following breast-conserving surgery for breast cancer is a significant failure of local treatment. This article reviews the mechanisms, risk factors and overall significance of such local recurrence. The presence of disease at excision margins, an extensive intraduct component, lymphatic vessel invasion, tumour grade and tumour size are currently the best predictors of risk for...

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Pattern of ipsilateral breast tumor recurrence after breast-conserving therapy.

PURPOSE To analyze the incidence and prognostic factors of ipsilateral breast tumor recurrence (IBTR) after breast-conserving therapy (BCT) in a large, population-based, single-center study with long-term follow-up. METHODS AND MATERIALS We analyzed 3595 cases in which BCT was performed in 3824 women with stage I or II breast cancer. The incidence of IBTR was analyzed over time and was based ...

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Ipsilateral breast tumor recurrence after breast-conserving therapy.

In the modern era of breast-conserving therapy for early-stage breast cancer, ipsilateral breast tumor recurrence (IBTR) represents an increasingly common clinical dilemma. Two kinds of IBTRs have been described: true recurrences, which represent regrowth of uneradicated initial disease, and new primaries, which may be distinct from the index lesion in histology and location. Whether these two ...

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Ipsilateral in-breast tumor recurrence after breast conserving therapy: true recurrence versus new primary tumor.

PURPOSE To classify ipsilateral in-breast cancer recurrences (IBCR) in patients treated with conservative surgery and radiation therapy, either as new primary tumor (NP) or true recurrence (TR) and to assess the prognostic and therapeutic importance of this classification. METHODS The records of 107 patients treated for local tu- mor recurrence after breast-conserving therapy (BCT) at the Nat...

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Prognostic Impact of Time to Ipsilateral Breast Tumor Recurrence after Breast Conserving Surgery

BACKGROUND The poor prognosis of patients who experience ipsilateral breast tumor recurrence (IBTR) after breast conserving surgery (BCS) is established. A short time between primary cancer and IBTR is a prognostic factor but no clinically relevant threshold was determined. Classification of IBTR may help tailor treatment strategies. PURPOSE We determined a specific time frame, which differen...

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ژورنال

عنوان ژورنال: Breast Cancer Research and Treatment

سال: 2008

ISSN: 0167-6806,1573-7217

DOI: 10.1007/s10549-008-0187-y